Is YouTube the new venue for exposing research misconduct?

“An anonymous whistleblower has created a YouTube video that details alleged duplication of images by a prominent Japanese scientist.

“The nearly 6-minute video, complete with background music, presents a series of still shots of over 60 allegedly duplicated and manipulated images in 24 papers, including 19 instances in a single publication, by a group led by molecular signaling specialist Shigeaki Kato of the University of Tokyo’s Institute of Molecular and Cellular Biosciences. The publications go back to 2001, include numerous co-authors, and have appeared in NatureCell, the Proceedings of the National Academy of Sciences, and other journals…

via ScienceInsider

 

Moral Science: Protecting Participants in Human Subjects Research

Published by the Presidential Commission for the Study of Bioethical Issues, this report concluded that “current rules and regulations provide adequate safeguards to mitigate risk.” Nevertheless, the Commission also recommended 14 changes to the current system.

Free download of Moral Science: Protecting Participants in Human Subjects Research

 

 

Resources for Teaching Research Ethics

Beauchamp TL, Childress JF. Principles of Biomedical Ethics. Oxford Press, Oxford, (2001).

Promoting Responsible Conduct in Research through “Survival Skills” Workshops: Some Mentoring is Best Done in a Crowd. Fischer BA and Zigmond MJ. Science and Engineering Ethics, 2001, 7:4, 563-587.

Moral Reasoning in Scientific Research: Cases for Teaching and Assessment. Bebeau MJ, Pimple KD, Muskavitch KMT, Borden SL & Smith DH. Bloomington, IN: Indiana University, 1995; see www.indiana.edu/~poynter

Comstock GL. Life Sciences Ethics, Iowa State Press, 2002.

EthicShare

“A research and collaboration website designed to help you do research, share, collaborate, and participate in the field of ethics. It includes…research materials, group discussions, current news articles, and upcoming events.”

Onlineethics.org

Has a large collection of ethics cases.

The Lab Office of Research Integrity.

An extremely well done interactive video that deals with issues of research integrity. Can be viewed by students on their own or used as a stimulus for class discussion. Also see the ORI website for other resources.

Bioethics at the movies. Sapshay S (ed). Johns Hopkins University Press, (2010).

Science & Engineering Ethics

A peer-reviewed journal that publishes original research articles as well as articles on teaching research ethics.

Scientific Integrity: An Introductory Text with Cases, 3rd edition. Macrina, FL. ASM Press, 2005.

Policies on Research Ethics

45 CFR part 46 (DHHS regulations on the use of human subjects in research.

Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research

National Institutes of Health. (2009)  Update on the Requirement for Instruction in the Responsible Conduct of Research. (NOT-OD-10-019)

Society for Neuroscience. Guidelines: Responsible Conduct Regarding Scientific Communication.

World Medical Association. Declaration of Helsinki.

Ethics and Human Subjects in Research (selected resources)

45 CFR part 46

DHHS regulations on the use of human subjects in research.

Belmont Report

Korenman, S. Teaching the Responsible Conduct of Research in Humans.

National Institutes of Health. Decision Tree for Protection of Human Subjects from Research Risk.

National Institutes of Health, Office of Extramural Research. OER Human Subjects Website

Pence GE. Classic Cases in Medical Ethics: Accounts of Cases that Have Shaped Medical Ethics, with Philosophical, Legal, and Historical Backgrounds. NY, NY, McGraw-Hill, 2004.

World Medical Association. Declaration of Helsinki.

Ethics and Use of Animals in Research (selected resources)

American Psychological Association. Research with Animals in Psychology

Chimpanzees in Biomedical Research: Assessing the Necessity. National Academies Press (2011).

Institute for Animal Laboratory Research (ILAR)Guide to the Care and Use of Laboratory Animals, 8th edition (2011).

Journal of Animal Ethics

National Institutes of Health, Office of Laboratory Animal Welfare (OLAW)

Top Science Scandals of 2011

“Science is no stranger to controversy. This year, some high profile scientists have been accused of widespread misconduct, while other headline-grabbing research has been retracted after technical errors or sloppy techniques were pointed out by critics.The scientific field may deal with aftershocks of the misconduct or retraction for years.

“Here are five of the biggest science scandals of the year, as well as updates on some of the juiciest scandals of years past.”

From The Scientist

Guidance for the Description of Animal Research in Scientific Publications


Guidance for the Description of Animal Research in Scientific Publications 

(Free PDF download from the NAS website!)

Publisher’s description:

“The publication of research articles involving animal studies is central to many disciplines in science and biomedicine. Effective descriptions in such publications enable researchers to interpret the data, evaluate and replicate findings, and move the science forward. (more…)

Animal Research in a Global Environment

Animal Research in a Global Environment: Meeting the Challenges: Proceedings of the November 2008 International Workshop. National Academy of Sciences, 2011.

Free PDF download from the NAS website!

Publisher’s description:

“Animal research will play an essential role in efforts to meet increasing demands for global health care. Yet the animal research community faces the challenge of overcoming negative impressions that industry and academia engage in international collaborations in order to conduct work in parts of the world where animal welfare standards are less stringent. Thus, the importance of ensuring the international harmonization of the principles and standards of animal care and use cannot be overstated. (more…)

Final Rule on Conflict of Interest (DHHS)

DHHS has released an updated Final Rule on Conflict of Interest, known officially as the “Responsibility of Applicants for Promoting Objectivity in Research for  which Public Health Service Funding is Sought and Responsible Prospective Contractor” (whew!) in the Federal Register, Vol. 76, No. 165, 25 August 2011.